Pharmacokinetics: is define as what the body do to the drugs when taken into the body system, while Pharmacodynamics explain what action dose the drug take on the body system. There are four pharmacokinetic that explain general information of drugs taken into the systems, they are absorption, distribution, metabolism, and elimination.

Drugs Mechanism in the body system

Absorption: First, absorption from the site of administration permits entry of the drug (either directly or indirectly) into plasma.

Distribution: Second, the drug may then reversibly leave the bloodstream and distribute into the interstitial and intracellular fluids.

Metabolism: Third, the drug may be bio transformed by metabolism by the liver or other tissues.

Elimination: Finally, the drug and its metabolites are eliminated from the body in urine, bile, or feces. Using knowledge of pharmacokinetic parameters, clinicians can design optimal drug regimens, including the route of administration, the dose, the frequency, and the duration of treatment. COLITIS, ULCERATIVE (UC)